Dr. Wolfgang Sommergruber

Wolfgang Sommergruber studied Biochemistry at the University of Vienna, Austria, and received his Magister in 1981 and his Ph.D. in 1985. During the time as a Postdoc at the Institute of Biochemistry (Medical Faculty) and a short- term research fellowship at Stony Brook University, New York, his scientific focus was on the molecular characterization of the proteolytic processing of picornaviruses. In 1986 he joined as a lab head Boehringer Ingelheim in Vienna, Austria, where he performed research on viral and tumor-associated proteases. These studies served as the basis for his habilitation thesis, and Wolfgang received the "Venia Docendi" for Medical Biochemistry in 2000. From 2002 till 2019 he worked as a Scientific Director in the Dept. of Exploratory Research Oncology at Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria. During this time Wolfgang performed translational research on the transcriptional control of interferon genes and the identification of novel tumor-associated antigens by combination of subtractive libraries with cDNA microarrays. Later on, Wolfgang aimed at the identification of novel drug intervention sites in oncology including targets in tumor metabolism, tumor-stroma crosstalk, epigenetic targets in immune-oncology and immunogenic cell death. Since 2019 he is Visiting Professor at University of Applied Sciences, Vienna, Austria. Wolfgang got several awards and was leader and co-leader in international and national research programs such as GEN-Au (Austrian Genomic Research Program - "Genomic Approaches to Tumor Invasion and Metastasis"; 2002-2006) and IMI (Innovative Medicines Initiative - "New tools for target validation to improve drug efficacy" embedded in the European FP7 program; 2011-2016). Wolfgang is (co)author of 80 peer-revied publications and 9 book chapters. He was invited for lectures at 50 international and national congresses. In 2021 he joined wings4innovation GmbH as Translational Guide.